The MoleculeDx Test

Everything you need to know about our Fusion-detect™ blood-based liver cancer screening test.

 

What We Test For

Detecting HCC Before Symptoms Appear

The MoleculeDx test screens specifically for hepatocellular carcinoma (HCC) — the most common form of primary liver cancer, accounting for 75–85% of all liver cancer cases in the US.

We analyze circulating tumor DNA (ctDNA) in your blood for HCC-specific fusion gene signatures. These molecular markers appear in the bloodstream at very early tumor stages — often 12–18 months before imaging can detect a tumor.

Who should get tested? Anyone with risk factors including: chronic hepatitis B or C, cirrhosis, non-alcoholic fatty liver disease (NAFLD/NASH), heavy alcohol use (past or present), family history of liver cancer, or Type 2 diabetes with liver disease.

Performance Data

Clinical Validation Results

MetricFusion-detect™ (MoleculeDx)Standard AFP TestUltrasound Alone
Overall Accuracy96.7%~52%~63%
Sensitivity (Early Stage)94.2%~41%~47%
Specificity98.1%~87%~91%
Detects Stage I HCC✓ YesOften NoOften No
Invasive ProcedureNoneNoneHospital Req.
At-Home Collection✓ YesNoNo
Result Turnaround24 Hours24–48 hrs1–2 weeks
The MoleculeDx test is a screening tool, not a diagnosis. A positive result will be followed up with your physician to confirm findings via imaging or specialist consultation.

Pricing

Transparent, Affordable Pricing

No hidden fees. No surprise bills. And our team will verify your insurance coverage for free before you schedule.

Most Popular

Home Visit

$160 / test

Single liver cancer screening test with full digital report.

Most Affortable

Visit UPMC

Custom  / test

Single liver cancer screening test with full digital report.

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The Moleculedx cancer test analyses molecular biomarkers in a patient sample to help detect, characterise or monitor cancer-related changes. The exact biomarkers and target conditions vary by test panel — full details are listed on each test’s specification page.

 Moleculedx offers panels covering a range of common cancers, including but not limited to breast, lung, colorectal, prostate and gynaecological cancers. Each panel page lists the exact conditions covered and clinical context.

Depending on the test panel, samples may include blood (venous draw), saliva, urine, or, in some cases, tissue. The required sample type is clearly indicated when you book and is communicated again before sample collection.

Most Moleculedx tests use minimally invasive samples like blood draws, saliva or urine. A blood draw involves brief, mild discomfort similar to any standard blood test. Tissue-based tests are only used where clinically required and follow standard medical procedures.

Each Moleculedx panel is clinically validated and reports defined sensitivity and specificity values for the conditions it screens. The exact accuracy metrics are listed on the corresponding test page so you can review them before booking.

Different Moleculedx panels serve different clinical purposes — some are screening (early-detection) panels, others are diagnostic adjuncts, and others support monitoring of an established condition. The intended use is stated on every test page and report.
No medical test is 100 percent accurate. Like all clinical tests, Moleculedx tests carry a small probability of false positives and false negatives within the limits described in the test specification. Doctors interpret results in the context of clinical findings and other investigations.
Each report is structured into patient details, test summary, biomarker findings, clinical interpretation, and a recommended next-step note where applicable. Reports are reviewed and signed off by qualified clinical specialists before release.
Always discuss your report with a qualified physician. Moleculedx can also connect you to a partner clinical advisor for an initial conversation if you have not yet engaged a doctor. A positive or unclear result usually requires confirmatory testing or follow-up imaging.

Frequency depends on the test, your age, family history and clinical risk factors. Some screening tests are recommended annually, others less frequently. Your doctor or a Moleculedx clinical advisor can help define the right interval for you.

Some panels are intended only for specific age groups, sexes or risk categories. The eligibility criteria are listed on the test page, and our team will flag any restrictions during the booking process.

Moleculedx tests use molecular signals from minimally invasive samples and are typically faster and less invasive than a tissue biopsy or imaging study. They are designed to complement, not replace, your doctor’s broader diagnostic workup, which may still include imaging or biopsy when clinically necessary.