For Providers – MoleculeDX

For Healthcare Providers

Partner with MoleculeDx to offer your at-risk patients best-in-class HCC surveillance without adding clinical burden.

Clinical Integration

Designed to Fit Your Practice

Our provider program integrates seamlessly with existing clinical workflows. Order tests, track results, and receive actionable alerts — all within your existing systems.

Simple Test Ordering

Order MoleculeDx tests directly from your EHR via HL7/FHIR integration or our lightweight web portal. CPT coding and billing support included.

EHR Results Delivery

Results are delivered directly to your preferred EHR system within 24 hours. Flags and abnormal results trigger real-time provider alerts via your preferred channel.

Patient Coordination

We handle all patient communication, scheduling, and home visit logistics. Your team only needs to order the test — we manage the rest.

Population Health Dashboard

Track screening compliance across your entire at-risk patient panel. Identify gaps, set reminders, and report on program performance — all in one dashboard.

UPMC Clinical Protocol

As our flagship clinical partner, UPMC has developed a full integration protocol for the MoleculeDx test. We work with UPMC’s oncology team on all positive result referrals.

Reimbursement Support

Our billing team handles prior authorization, insurance verification, and appeals for denied claims. We maximize reimbursement so your patients face minimal out-of-pocket cost.

UPMC Partnership

How the UPMC Integration Works

1 Physician Referral or Walk-In

UPMC physicians can order the test via the UPMC Epic integration, or patients can self-refer by walking in to any UPMC facility and requesting the MoleculeDx liver cancer screen.

2 On-Site or Home Collection

At UPMC sites with phlebotomy services, the blood draw is performed on-site. For patients who prefer at-home collection, Portamedic or Travalab is dispatched to their address.

3 Results in UPMC Epic

Results are returned within 24 hours directly to the patient’s UPMC Epic record. Abnormal results trigger automatic alerts to the ordering physician and UPMC Hepatology.

Partner With Us

Ready to set up MoleculeDx in your practice or health system? Our clinical partnerships team can have you onboarded in under a week.

Are You at Risk?

Liver Cancer Risk Factors

You may benefit from regular liver cancer screening if you have one or more of these conditions.

What exactly does the MoleculeDx test screen for?

The test screens for hepatocellular carcinoma (HCC) — the most common form of primary liver cancer. We analyze your blood for fusion gene biomarkers that are specific to early-stage liver cancer. These markers appear in the bloodstream significantly earlier than tumors become visible on ultrasound or CT scans.

Is the test painful? What does "at-home blood draw" involve?

The test requires only a standard venipuncture — the same blood draw you’d receive at any clinic or doctor’s office. It is not a biopsy. There’s no tissue removal, no surgery, and no imaging. Most people describe it as mild and brief. The certified phlebotomist comes to your home and the draw itself takes 5–10 minutes.

How accurate is the test? How does it compare to a biopsy?

The Fusion-detect™ test achieves 96.7% overall accuracy, 94.2% sensitivity, and 98.1% specificity in clinical validation. A liver biopsy is considered definitive for diagnosis — but it is invasive, carries risks of bleeding and infection, and is not suitable as a screening tool. Our test is a screening tool that identifies patients who need further investigation. For a positive MoleculeDx result, we facilitate referral to a physician for confirmatory imaging or biopsy if warranted.

Does my insurance cover the test?

MoleculeDx is accepted by most major US insurers including UnitedHealth, Anthem/Blue Cross Blue Shield, Aetna, Cigna, Humana, and UPMC Health Plan. Medicare Advantage plans are also accepted. Coverage for cancer screening tests varies by plan and diagnosis code. Our team will verify your specific coverage for free before you book — contact us or check at booking.moleculedx.com.

How quickly will I get my results?

Results are delivered digitally within 24 hours of sample receipt at our laboratory. You’ll receive a secure notification by email or SMS with access to your full clinical report. For results that require attention, a care coordinator will reach out to you directly within the same window to guide next steps.

What happens if my result is positive?

A positive result does not mean you have cancer — it means biomarkers were detected that warrant further evaluation. Our care coordinator will contact you immediately to explain your results in plain language and help arrange follow-up imaging (typically an MRI or CT) and referral to a hepatologist or oncologist. We work with your existing providers or can refer you to UPMC specialists depending on your location.

Can I walk in to a UPMC location for testing?

Yes. Through our exclusive partnership with University of Pittsburgh Medical Center, patients can walk into any UPMC facility and request the MoleculeDx liver cancer screening test. UPMC physicians can also order it directly through UPMC’s Epic EHR system. Results are delivered within 24 hours and integrated directly into your UPMC health record.

Who are your phlebotomy partners and are they certified?

We partner with Portamedic (portamedic.com) and Travalab (travalab.com) — two of the largest and most trusted mobile phlebotomy networks in the United States. All phlebotomists are nationally certified (CPT or equivalent) and undergo background checks and quality assurance training specific to MoleculeDx sample handling protocols.

Do I need a doctor's referral to book a test?

No referral is required to book a self-pay test. However, insurance coverage typically requires an ordering physician. If you don’t have a primary care provider, our care coordinators can help connect you with a telemedicine physician who can provide the order — often within the same day.

Is the test available everywhere in the US?

At-home phlebotomy through Portamedic and Travalab is available across all 50 US states, though coverage in rural areas may require advance scheduling of 3–5 days. Walk-in testing is currently available exclusively at UPMC locations. We are actively expanding our clinical site network — check booking.moleculedx.com for your specific zip code coverage.