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For Patients

We’ve designed every part of this test to be as simple as possible — because your health shouldn’t require a medical degree to manage.

Are You at Risk?

Liver Cancer Risk Factors

You may benefit from regular liver cancer screening if you have one or more of these conditions.

Hepatitis B or C

Chronic viral hepatitis is the leading cause of liver cancer globally. If you’ve been diagnosed with hepatitis B or C, regular screening is strongly recommended by the ACS and AASLD.

Alcohol-Related Liver Disease

Long-term heavy alcohol use can lead to cirrhosis, which significantly raises the risk of developing hepatocellular carcinoma even after stopping drinking.

Non-Alcoholic Fatty Liver (NAFLD)

One of the fastest-growing risk factors in the US. NAFLD and NASH can progress to cirrhosis and liver cancer — especially combined with Type 2 diabetes or obesity.

Cirrhosis (Any Cause)

Regardless of cause, cirrhosis significantly elevates liver cancer risk. Guidelines recommend HCC surveillance every 6 months for all cirrhosis patients.

Family History

If a first-degree relative (parent, sibling, child) has had liver cancer, your risk is meaningfully elevated. Consider early and regular screening.

Diabetes & Metabolic Syndrome

Type 2 diabetes and metabolic syndrome are independent risk factors for HCC. Combined with any liver condition, the risk increases substantially.

The Experience

What to Expect on Test Day

Before Your Appointment

You’ll receive a confirmation email with prep instructions. No fasting required in most cases. A certified phlebotomist will call 30 minutes before arrival.

The Home Visit

Your phlebotomist typically arrives in a 2-hour window you selected. The blood draw takes 5–10 minutes. It’s a standard venipuncture — the same as a routine blood test at any clinic.

Your Sample

The sample is sealed and transported to our CLIA-certified laboratory via temperature-controlled courier within hours of collection — maintaining integrity for the most accurate results.

Your Results

Within 24 hours, you’ll receive a secure notification with your full digital report. If your results require attention, a care coordinator will contact you directly — no waiting alone.

Ready to Take Control of Your Liver Health?

Booking takes 2 minutes. A phlebotomist can be at your door within 48 hours. Don’t wait for symptoms that may never come.

Book Your Test
Read the FAQ

Are You at Risk?

FAQ 

You may benefit from regular liver cancer screening if you have one or more of these conditions.

The test screens for hepatocellular carcinoma (HCC) — the most common form of primary liver cancer. We analyze your blood for fusion gene biomarkers that are specific to early-stage liver cancer. These markers appear in the bloodstream significantly earlier than tumors become visible on ultrasound or CT scans.

The test requires only a standard venipuncture — the same blood draw you’d receive at any clinic or doctor’s office. It is not a biopsy. There’s no tissue removal, no surgery, and no imaging. Most people describe it as mild and brief. The certified phlebotomist comes to your home and the draw itself takes 5–10 minutes.
 
The Fusion-detect™ test achieves 96.7% overall accuracy, 94.2% sensitivity, and 98.1% specificity in clinical validation. A liver biopsy is considered definitive for diagnosis — but it is invasive, carries risks of bleeding and infection, and is not suitable as a screening tool. Our test is a screening tool that identifies patients who need further investigation. For a positive MoleculeDx result, we facilitate referral to a physician for confirmatory imaging or biopsy if warranted.
 
MoleculeDx is accepted by most major US insurers including UnitedHealth, Anthem/Blue Cross Blue Shield, Aetna, Cigna, Humana, and UPMC Health Plan. Medicare Advantage plans are also accepted. Coverage for cancer screening tests varies by plan and diagnosis code. Our team will verify your specific coverage for free before you book — contact us or check at booking.moleculedx.com.
 
Results are delivered digitally within 24 hours of sample receipt at our laboratory. You’ll receive a secure notification by email or SMS with access to your full clinical report. For results that require attention, a care coordinator will reach out to you directly within the same window to guide next steps.
 
A positive result does not mean you have cancer — it means biomarkers were detected that warrant further evaluation. Our care coordinator will contact you immediately to explain your results in plain language and help arrange follow-up imaging (typically an MRI or CT) and referral to a hepatologist or oncologist. We work with your existing providers or can refer you to UPMC specialists depending on your location.
 
Yes. Through our exclusive partnership with University of Pittsburgh Medical Center, patients can walk into any UPMC facility and request the MoleculeDx liver cancer screening test. UPMC physicians can also order it directly through UPMC’s Epic EHR system. Results are delivered within 24 hours and integrated directly into your UPMC health record.
 
We partner with Portamedic (portamedic.com) and Travalab (travalab.com) — two of the largest and most trusted mobile phlebotomy networks in the United States. All phlebotomists are nationally certified (CPT or equivalent) and undergo background checks and quality assurance training specific to MoleculeDx sample handling protocols.
 
No referral is required to book a self-pay test. However, insurance coverage typically requires an ordering physician. If you don’t have a primary care provider, our care coordinators can help connect you with a telemedicine physician who can provide the order — often within the same day.
 
At-home phlebotomy through Portamedic and Travalab is available across all 50 US states, though coverage in rural areas may require advance scheduling of 3–5 days. Walk-in testing is currently available exclusively at UPMC locations. We are actively expanding our clinical site network — check booking.moleculedx.com for your specific zip code coverage.
 

First-in-class blood-based liver cancer early detection. Powered by Fusion-detect™ AI genomics technology.

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© 2026 MoleculeDx Inc. All rights reserved.

This test is not a substitute for medical diagnosis. Consult your physician with all results.